Browse peer-reviewed studies from PubMed with plain-language summaries. Search by keyword or filter by peptide.
Peptides are short chains of amino acids that act as signaling molecules in the body, influencing processes like hormone regulation, immune response, and tissue repair. Researchers are studying them for applications ranging from metabolic health to neuroprotection. Pepdox collects peer-reviewed studies from PubMed and pairs them with plain-language summaries so you can follow the science yourself.
Warning: Most peptides are not approved by the FDA for human use and are sold for research purposes only. Self-administering peptides carries real risks including contamination, incorrect dosing, and unknown long-term side effects. Nothing on this site is medical advice.
A synthetic peptide fragment of thymosin beta-4, researched for wound healing and tissue repair.
A dual GIP and GLP-1 receptor agonist approved for type 2 diabetes and obesity.
A synthetic pentadecapeptide derived from human gastric juice, studied for its regenerative and protective properties.
A mitochondria-derived peptide encoded in the mitochondrial 12S rRNA, studied for its roles in metabolic regulation, insulin sensitivity, and longevit…
NLRP3 functions as a critical intracellular danger sensor for inflammasome activation, playing a crucial role in autoimmune diseases. Vitiligo progression has been linked to NLRP3, yet its specific involvement in melanocytes of vitiligo remains poorl…
Oral delivery of peptide therapeutics remains challenging due to gastrointestinal (GI) degradation and poor intestinal absorption. Here, we propose a self-immolative peptide prodrug conjugate (SIPPC) platform for inflammation-targeted oral delivery,…
Primary mitochondrial myopathies (PMMs), a group of genetic mitochondrial oxidative phosphorylation disorders, primarily affect skeletal muscle function. No approved treatments for PMM exist, and patient information is limited. The international RePO…
Diabetes mellitus impairs the regenerative capacity of valvular patients and poses a major barrier to successful reconstruction of autologous heart valves via in situ tissue-engineered heart valves (TEHVs). Herein, we developed a TEHV scaffold that i…
Accumulating evidence suggests that ferroptosis and mitochondrial dysfunction contribute significantly to brain injury following cardiac arrest (CA) and resuscitation. SS-31, a novel mitochondria-targeting peptide, has demonstrated protective effects…
BACKGROUND: The ream-and-run arthroplasty (RnR) has shown to be a viable treatment option for young, active patients with shoulder osteoarthritis. However, there are notable concerns with the generalizability of these findings as much of the literatu…