Failure of a Meta-analysis: A Commentary on Glen Spielmans's "Re-Analyzing Phase III Bremelanotide Trials for 'Hypoactive Sexual Desire Disorder in Women'".

Plain Language Summary

A response to Glen Spielmans' re-analysis (PMID 33678061) criticizing the bremelanotide phase 3 trials. Defends the statistical validity and clinical meaningfulness of the RECONNECT trial outcomes, arguing that the re-analysis drew unwarranted conclusions from the same data.