Compares effect sizes of pharmacological (testosterone, flibanserin, bremelanotide) vs. psychological (CBT, mindfulness) interventions for HSDD in women. Finds that both the active drug effects and placebo effects are larger for medications than previously assumed, and that drug effect sizes are comparable to psychotherapy effect sizes. Provides context for evaluating bremelanotide's clinical meaningfulness.
Pyke, Robert E; Clayton, Anita H